Teeth & Brain: The Surprising Connection

For a long time, brushing your teeth was thought to be only about keeping a nice smile and avoiding cavities. But recent research reveals a surprising connection between oral health and neurodegenerative diseases like Alzheimer’s.

🧐 The villain?

A bacterium called Porphyromonas gingivalis, the main culprit behind periodontal disease (gingivitis and periodontitis). This bacterium, commonly found in the mouths of people with gum inflammation, has been detected in the brains of Alzheimer’s patients in several international studies. Even more alarming: evidence suggests it may be involved in the development of the disease years before the first symptoms of memory loss appear.

👨‍🎓 What science is discovering:

• P. gingivalis was identified in up to 96% of studied brains from people with Alzheimer’s.

• This bacterium releases toxins called gingipains, which destroy neurons and promote the buildup of toxic proteins like beta-amyloid—the main hallmark of Alzheimer’s.

• In animal studies, infection with the bacterium led to memory loss, brain inflammation, and changes similar to human Alzheimer’s.

• A new experimental drug, COR388 (atuzaginstat), has shown potential to block these toxins and slow the disease’s progression in early trials.

✅ Prevention starts with your toothbrush

🔥The good news is that something as simple as brushing your teeth, flossing, and visiting the dentist regularly may help protect not just your mouth—but also your mind.

It’s no longer just about aesthetics or comfort. We’re talking about your quality of life in the future.

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